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Generic Name: diltiazem (dil TYE a zem)
Brand Names: Cardizem, Cardizem CD, Cardizem LA, Cardizem SR, Cartia XT, Dilacor XR, Diltia XT, Tiazac

Cardizem : Important Information

• Use caution when driving, operating machinery, or performing other hazardous activities. Cardizem may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.
• Do not stop taking this medication without first talking to your doctor. If you stop taking your medication, your condition could become worse.
• Follow any diet or exercise recommendations for your condition.
• Do not open, break, crush, or chew any extended-release forms of this medication. Swallow them whole.

What is Cardizem

• In a class of drugs called calcium channel blockers. This medication relaxes (widens) your blood vessels (veins and arteries), which makes it easier for your heart to pump and reduces the workload on it.
• Used to treat hypertension (high blood pressure), to treat angina (chest pain), and to slow unusually fast heartbeats.

What to Discuss before Using

• Before taking this medication, tell your doctor if you have:
  • ever had an allergic reaction to any form of diltiazem in the past
  • kidney disease
  • liver disease
  • other diseases of the heart or blood vessels such as sick sinus syndrome, aortic stenosis, congestive heart failure, heart block, low blood pressure, or coronary artery disease
• You may not be able to take this medication, or you may require a special dosage or monitoring during treatment if you have any of the conditions listed above.
• Talk to your doctor about consuming grapefruit or grapefruit juice while you are taking this medication as it can interact with grapefruit and grapefruit juice and the interaction may have dangerous effects.
• In the FDA pregnancy category C. This means that it is not known whether this medication will be harmful to an unborn baby. Do not take without first talking to your doctor if you are pregnant or could become pregnant during treatment.
• Passes into breast milk and may affect a nursing infant. Do not take without first talking to your doctor if you are breast-feeding a baby.

Cardizem Dosage Method

• Take exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.
• Take each dose with a full glass of water.
• Do not open, break, crush, or chew any extended-release forms of this medication such as Cardizem CD, Cardizem LA, Cardizem SR, Cartia XT, Diltia XT, or Dilacor XR. Swallow them whole.
• If swallowing is difficult, the Tiazac capsules may be opened and the contents sprinkled onto a spoonful of applesauce. The applesauce should be swallowed immediately, without chewing, and followed with a glass of water to ensure complete swallowing of the capsule contents. The applesauce should not be hot and should be soft enough to enable swallowing without chewing. The mixture must be consumed immediately and not stored for later use.
• Dilacor XR and Diltia XT should be taken in the morning on an empty stomach.
• It is important to take this medication regularly to get the most benefit.
• Do not stop taking this medication without first talking to your doctor. If you stop taking the medication, your condition could become worse.
• Your doctor may want you to have blood tests, blood pressure monitoring, or other medical evaluations during treatment to monitor progress and side effects.
• Store at room temperature away from moisture and heat.

Miss a dose: Problems?

Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication.

Cardizem Overdose?

• Seek emergency medical attention if an overdose is suspected.
• Symptoms of an overdose include dizziness, weakness, chest pain, shortness of breath, fainting, an unusually fast or slow heartbeat, coma, slurred speech, and confusion.

Avoid During Treatment

• Use caution when driving, operating machinery, or performing other hazardous activities. This medication may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.
• Use alcohol cautiously. Alcohol may further lower blood pressure and increase drowsiness and dizziness while taking this medication.
• Follow any recommendations your doctor makes about diet or exercise.

Cardizem Side Effects

• If you experience any of the following serious side effects, stop taking this medication and contact your doctor immediately or seek emergency medical treatment:
  • an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives)
  • unusually fast or slow heartbeats
  • severe dizziness or fainting
  • abnormal behavior or psychosis
  • jaundice (yellowing of the skin or eyes)
  • swelling of the legs or ankles
• Other, less serious side effects may be more likely to occur. Continue to take this medication and talk to your doctor if you experience:
  • fatigue or tiredness
  • headache
  • flushing (redness)
  • insomnia and vivid dreams
  • nausea, diarrhea, or constipation
  • difficulty urinating
  • numbness
  • a rash
• Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs to avoid while undergoing treatment

• Before taking this medication, tell your doctor if you are taking any of the following medicines:
  • other medicines to treat the same or another heart condition
  • cyclosporine (Sandimmune, Neoral)
  • cimetidine (Tagamet, Tagamet HB)
  • carbamazepine (Tegretol)
  • digoxin (Lanoxin)
  • midazolam (Versed) or triazolam (Halcion)
  • rifampin (Rifadin, Rimactane) or rifabutin (Mycobutin)
• You may not be able to take this medication, or you may require a special dosage if you are taking any of the medicines listed above.
• Talk to your doctor about consuming grapefruit or grapefruit juice while you are taking this medication as it can interact with grapefruit and grapefruit juice and the interaction may have dangerous effects.
• Drugs other than those listed here may also interact or affect your condition. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

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