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Generic Name: alendronate (a LEN droe nate)
Brand Names: Fosamax

Fosamax : Important Information

  • Some forms of Fosamax are taken once a day. Others are taken only once a week. It is very important that you follow your doctor's directions. If you take Fosamax once a week, take it on the same day each week.
  • After swallowing the Fosamax tablet or oral solution, do not lie down, remain fully upright sitting, standing or walking, for at least 30 minutes and until after you have eaten.
  • Do not take at bedtime or before getting up for the day.
  • Do not crush, chew, or suck the Fosamax tablets. Swallow them whole.

What is Fosamax

  • A compound that alters the cycle of bone formation and breakdown in the body.
  • Fosamax increases new bone formation.
  • Fosamax is used to treat and prevent osteoporosis and to treat Paget's disease. Also used to treat osteoporosis that is caused by treatment with a corticosteroid.

What to Discuss Before Using Fosamax

  • Before taking Fosamax, tell your doctor if you:
    • have a problem swallowing, such as a narrowing of the esophagus
    • have esophageal ulcers or an esophageal disease
    • have a condition that causes low levels of calcium in the body
    • have kidney disease
    • have stomach ulcers or other stomach or digestive problems
    • are unable to stand or sit upright for at least 30 minutes
  • You may not be able to take Fosamax, or you may require a special dosage or monitoring during treatment if you have any of the conditions listed above.
  • Fosamax belongs to the FDA pregnancy category C. This means that it is not known whether this medication will be harmful to an unborn baby. Do not take without first talking to your doctor if you are pregnant or could become pregnant during treatment.
  • It is not known whether this medication passes into breast milk. Do not take without first talking to your doctor if you are breast-feeding a baby.

Fosamax Dosage Method

  • Take Fosamax exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.
  • Some forms of Fosamax are taken once a day. Others are taken only once a week. It is very important that you follow your doctor's directions. If you take medicine once a week, take it on the same day each week.
  • Take first thing in the morning, at least 30 minutes before you eat any food or drink any liquid (other than plain water). This timing is very important for getting the maximum amount of medication from each dose. Foods and beverages greatly decrease the effect.
  • To ensure that you get a correct dose, measure the oral suspension with a dose-measuring spoon, dropper, or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one.
  • Take each Fosamax tablet with a full glass of tap water or bottled water. Follow each dose of oral solution with at least 2 ounces of water. Taking each dose with a full glass of water will ensure proper swallowing of the medication and reduce the risk of mouth or throat irritation. Do not take this medication with mineral water, juice, or any other beverage.
  • Do not crush, chew, or suck the tablets. Swallow them whole.
  • After swallowing the Fosamax tablet or oral solution, do not lie down. Remain fully upright sitting, standing or walking, for at least 30 minutes and until after you have eaten.
  • Do not take at bedtime or before getting up for the day.
  • If you have difficulty or pain upon swallowing, chest pain, or new or worsening heartburn, stop taking medication and call your doctor.
  • It is important that you continue taking medication for as long as your doctor prescribes it, as it can treat or prevent osteoporosis only if you continue to take it.
  • Store Fosamax at room temperature away from moisture and heat.

Miss a dose: Problems?

  • If you take medication every day and you miss a dose, skip that dose and take the next regularly scheduled dose the following day. Missing one dose will not affect your treatment. Do not take two Fosamax tablets at the same time.
  • If you take medication once a week and you miss a dose, take the missed dose on the morning after you remember. Do not take two tablets on the same day. Return to taking one tablet once a week, as originally scheduled on your chosen day.

Fosamax Overdose?

  • Seek emergency medical attention if an overdose is suspected.
  • The symptoms of an overdose are unknown, but the following symptoms might be expected: nausea, heartburn, pain in the abdomen, other stomach-related symptoms, muscle cramps, uncontrollable facial grimacing, seizures, irritability, and abnormal behavior.

Avoid During Treatment

Follow you doctor's recommendations about drinking alcohol and smoking. These activities are related to decreased bone density.

Fosamax Side Effects

  • Stop taking Fosamax and seek emergency medical attention or contact your doctor immediately if you experience any of the following serious side effects:
    • an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives)
    • difficulty or pain when swallowing
    • chest pain
    • pain or burning under the ribs or in the back
    • new or worsening heartburn
  • Other, less serious side effects may be more likely to occur. Continue to take medication and talk to your doctor if you experience:
    • abdominal discomfort
    • stomach upset, nausea, vomiting, diarrhea, or constipation
    • headache
    • muscle, bone, or joint soreness or aches
    • eye pain
    • a rash
    • an altered sense of taste
  • Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs to avoid while undergoing treatment

  • Antacids and other medicines taken by mouth may decrease the effects of this medication. Do not take any other medicines within 30 minutes after a dose. Talk to your doctor before taking any other medicines during treatment.
  • Aspirin and nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Motrin, Advil, Nuprin, others), ketoprofen (Orudis KT, Orudis, Oruvail), indomethacin (Indocin, Indocin SR), naproxen (Anaprox, Aleve, Naprosyn), oxaprozin (Daypro), nabumetone (Relafen), piroxicam (Feldene), and others may increase the risk of damage to your stomach if they are taken during treatment. Talk to your doctor before taking anti-inflammatory medications, pain relievers or fever reducers during treatment.
  • Drugs other than those listed here may also interact. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

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