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Home >> RX Products >> Avandia (Rosiglitazone)

Avandia

Generic Name: rosiglitazone (oral) (row sih GLIH ta zone)
Brand Names: Avandia

Avandia : Important Information

  • Usually, liver function is monitored with blood tests at the start of treatment, every two months for the first year of treatment, and periodically thereafter during treatment. Notify your doctor immediately if you develop nausea, vomiting, abdominal pain, unusual fatigue, loss of appetite, yellow skin or eyes, or dark urine while using Avandia. These symptoms may be early signs of liver problems.
  • Notify your doctor immediately if you experience an unusually rapid increase in weight or edema (water retention), shortness of breath, or chest pain during treatment with Avandia. These may be early symptoms of heart problems.
  • Avandia usually does not cause hypoglycemia (low blood sugar). However, hypoglycemia may occur as a result of skipped meals, excessive exercise, or alcohol consumption during treatment. Know the signs and symptoms of hypoglycemia, which include headache, drowsiness, weakness, dizziness, fast heartbeat, sweating, tremor, and nausea. Carry non-dietetic hard candy or glucose tablets with you to treat episodes of low blood sugar.

What is Avandia

  • Avandia is an antihyperglycemic agent. It helps the body respond better to insulin and it reduces the amount of sugar produced by the liver. It can help control blood sugar levels.
  • Avandia medication is used, along with diet and exercise, in the treatment of type 2 diabetes. It may also be used with a sulfonylurea (e.g., Diabeta, Glucotrol, Micronase, others), metformin (Glucophage), or insulin when diet and exercise plus any one of these medicines alone do not result in adequate blood sugar control.

What to Discuss Before Using Avandia

  • Do not take Avandia drug without first talking to your doctor if you have liver disease.
  • Before taking Avandia, tell your doctor if you:
    • have heart failure or heart disease
    • have edema (water retention or swelling)
    • have type 1 diabetes mellitus
    • have a serious infection, illness, or injury
    • need surgery
  • You may not be able to take Avandia drug, or you may need a special dosage or monitoring during treatment if you have any of the conditions listed above.
  • Treatment may cause resumption of fertility by allowing for the return of ovulation (production of eggs) in certain women with insulin resistance who were not ovulating before treatment. Talk to your doctor about adequate forms of birth control while if birth control is desired.
  • Contact your doctor if you develop a fever or an infection, require surgery, or if you experience a serious injury. Illness or injury may cause a loss of blood sugar control and insulin (or an adjustment of a current insulin dose) may be required for a period of time.
  • In the FDA pregnancy category C. This means that it is not known whether this Avandia will harm an unborn baby. Generally, insulin is the drug of choice for controlling diabetes during pregnancy. Do not take this medication without first talking to your doctor if you are pregnant or could become pregnant during treatment.
  • It is not known whether Avandia passes into breast milk. Do not take without first talking to your doctor if you are breast-feeding a baby.
  • The safety and effectiveness of this drug have not been established for children.

Avandia Dosage Method

  • Take avandia exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.
  • Take each dose with a full glass of water.
  • Can be taken with or without food or meals.
  • It is important to take medication regularly to get the most benefit.
  • Your doctor may want you to have blood or urine tests or other medical evaluations during treatment to monitor blood sugar levels, liver function, or other factors.
  • Usually, liver function is monitored with blood tests at the start of treatment, every two months for the first year of treatment, and periodically thereafter during treatment. Notify your doctor immediately if you develop nausea, vomiting, abdominal pain, unusual fatigue, loss of appetite, yellow skin or eyes, or dark urine. These symptoms may be early signs of liver problems.
  • Although Avandia does not usually cause hypoglycemia (low blood sugar), hypoglycemia may result from skipped meals, excessive exercise, or alcohol consumption. Know the signs and symptoms of hypoglycemia, which include headache, drowsiness, weakness, dizziness, fast heartbeat, sweating, tremor, and nausea. Carry a piece of non-dietetic hard candy or glucose tablets with you to treat episodes of low blood sugar.
  • Store Avandia at room temperature away from moisture and heat.

Miss a dose: Problems?

Take the missed dose of Avandia as soon as you remember. If you do not remember until the next day, skip the dose you missed and take only your next regularly scheduled dose. Do not take a double dose.

Avandia Overdose?

  • Seek emergency medical attention if an overdose of Avandia is suspected.
  • Symptoms of an overdose are not known.

Avoid During Treatment

  • Follow your diet, medication, and exercise routines very closely. Changing any of these factors can affect your blood sugar levels.
  • Avoid alcohol. It lowers blood sugar and may interfere with your diabetes treatment.
  • Tell your doctor and dentist that you are taking this medication before you undergo any surgery.
  • Do not take any over-the-counter cough, cold, allergy, pain, or weight-loss medications without first talking to your doctor.

Avandia Side Effects

  • If you experience any of the following serious side effects, stop taking rosiglitazone and seek emergency medical attention or notify your doctor immediately:
    • an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives)
    • nausea, vomiting, abdominal pain, or loss of appetite
    • unusual fatigue
    • yellowing of the skin or eyes
    • dark urine
  • Notify your doctor immediately if you experience an unusually rapid increase in weight or edema (swelling, water retention), shortness of breath, or chest pain during treatment. These may be early symptoms of heart problems.
  • Although this medication does not usually cause hypoglycemia (low blood sugar), hypoglycemia may result from skipped meals, excessive exercise, or alcohol consumption. Know the signs and symptoms of hypoglycemia, which include headache, drowsiness, weakness, dizziness, fast heartbeat, sweating, tremor, and nausea. Carry a piece of hard non-dietetic candy or glucose tablets with you to treat episodes of low blood sugar.
  • Other less serious side effects may also occur. Continue to take this medication and talk to your doctor if you experience:
    • headache
    • sore throat, nasal discharge, or cold symptoms
  • Side effects other than those listed here may also occur due to use of Avandia. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs to avoid while undergoing treatment

No drugs have been reported to interact with this medication although interactions may exist. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

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Avandia (rosiglitazone) is an oral antidiabetic agent, which acts primarily by increasing insulin sensitivity. Avandia drug is used to hold down blood sugar levels in people with type 2 diabetes. Avandia medication helps your body respond better to insulin produced by your pancreas. Avandia is in a class of anti-diabetic drugs called thiazolidinediones. Avandia drug is normally taken once or twice daily, with or without meals.

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