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Cimetidine

Generic Name: cimetidine (sye MEH ti deen)
Brand Names: Tagamet, Tagamet HB

Cimetidine : Important Information

• Do not stop taking cimetidine without first talking to your doctor. It may take up to 8 weeks for an ulcer to heal.
• Do not take antacids within 1 hour of taking this medication. Antacids may decrease the effectiveness.

What is Cimetidine

• In a class of drugs called histamine receptor antagonists. This medication works by decreasing the amount of acid the stomach produces.
• Used to treat and prevent ulcers in the stomach and intestines. This medication is also used to treat conditions in which the stomach produces too much acid and conditions in which acid comes up into the esophagus and causes heartburn, such as gastroesophageal reflux disease (GERD).

What to Discuss before Using

• Before taking this medication, tell your doctor if you have:
  • kidney disease
  • liver disease
• You may not be able to take this medication, or you may require a special dosage or monitoring during treatment if you have any of the conditions listed above.
• In the FDA pregnancy category B. This means that it is unlikely to harm an unborn baby. Do not take without first talking to your doctor if you are pregnant.
• Passes into breast milk, but it is believed to have little effect on a nursing infant. Do not take without first talking to your doctor if you are breast-feeding a baby.

Cimetidine Dosage Method

• Take exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.
• Take each dose with a full glass of water.
• To ensure that you get the correct dose, measure the liquid forms with dose-measuring spoon or cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one.
• Do not stop taking this medication without first talking to your doctor. It may take up to 8 weeks for an ulcer to heal.
• Store at room temperature away from moisture and heat.

Miss a dose: Problems?

Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication unless otherwise directed by your doctor.

Cimetidine Overdose?

• Seek emergency medical attention.
• Symptoms of an overdose include nausea, vomiting, diarrhea, increased saliva production, difficulty breathing, and a fast heartbeat.

Avoid During Treatment

There are no restrictions on food, beverages, or activities while taking cimetidine, unless otherwise directed by your doctor.

Cimetidine Side Effects

• If you experience any of the following serious side effects, stop taking this medication and call your doctor immediately or seek emergency medical treatment:
  • an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives)
  • easy or unusual bruising or bleeding
  • bleeding gums
  • irregular heartbeat
  • yellowing of the skin
  • a rash
• Other, less serious side effects may be more likely to occur. Continue to take this medication and talk to your doctor if you experience:
  • dizziness
  • headache
  • diarrhea, nausea, or constipation
• Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome

What other drugs to avoid while undergoing treatment

• Do not take antacids within 1 hour of taking this medication. Antacids may decrease the effectiveness.
• Before taking this medication, tell your doctor if you are taking any of the following medicines:
  • a sedative, sleeping pill, or tranquilizer such as alprazolam (Xanax), diazepam (Valium), and chlordiazepoxide (Librium)
  • an anticoagulant (blood thinner) such as warfarin (Coumadin)
  • a seizure medication such as phenytoin (Dilantin) or carbamazepine (Tegretol)
  • a heart medication such as procainamide (Procan SR, Procanbid, Pronestyl), digoxin (Lanoxin), propranolol (Inderal), or metoprolol (Lopressor)
  • an oral diabetes medication such as glipizide (Glucotrol), glyburide (Diabeta, Micronase), tolbutamide (Tolinase), and others
  • ketoconazole (Nizoral), itraconazole (Sporanox), or fluconazole (Diflucan)
  • cisapride (Propulsid)
• You may not be able to take this medication, or you may require a special dosage or monitoring during treatment if you are taking any of the medicines listed above.
• Drugs other than those listed here may also interact. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

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