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Maxalt

Generic Name: rizatriptan (rye zah TRIP tin)
Brand Names: Maxalt, Maxalt-MLT

Maxalt : Important Information

• Do not take this medication if the headache you are experiencing is not like other migraines that you have had.
• Do not take this medication if you have angina (chest pain) or if you have had a heart attack.
• Never take more of this medication than is prescribed by your doctor. If your symptoms are not being treated, contact your doctor.

What is Maxalt

• A headache medicine. It is believed to work by causing vasoconstriction (narrowing) of arteries and veins that supply blood to your head.
• Used to treat vascular headaches such as migraine headaches.

What to Discuss before Using

• Do not take this medication if you:
  • have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), tranylcypromine (Parnate), or phenelzine (Nardil) in the last 14 days
  • have basilar or hemiplegic migraine headaches
  • have had a heart attack, have angina (chest pain), or have another type of heart disease
  • have had a stroke
  • have Raynaud's syndrome
  • are experiencing a headache that is not like other migraines that you have had
  • have taken another 5-HT agonist in the last 24 hours-5-HT agonists include almotriptan (Axert), frovatriptan (Frova), sumatriptan (Imitrex), naratriptan (Amerge), and zolmitriptan (Zomig, Zomig-ZMT)
  • have taken an ergot-based medication within the last 24 hours--ergot-based medicines include methysergide (Sansert), ergotamine (Ergostat, Ergomar), dihydroergotamine mesylate (D.H.E., Migranal Nasal Spray), and ergotamine combination products (Cafergot, Wigraine, Cafatine-PB, and others)
• It may be dangerous to take this medication if you have any of the conditions or are taking any of the medications listed above.
• Before taking this medication, tell your doctor if you:
  • have risk factor for heart disease such as high blood pressure, a family history of heart disease, high cholesterol (a type of fat), are overweight, diabetes, smoke cigarettes, are postmenopausal, are male and over 40 years of age
  • have liver disease
  • have kidney disease
  • have seizures or epilepsy
• You may not be able to take this medication, or you may require a special dosage or monitoring during treatment if you have any of the conditions listed above.
• The orally disintegrating tablets contain phenylalanine. Each 5 mg tablet contains 1.05 mg phenylalanine and each 10 mg tablet contains 2.10 mg phenylalanine. Individuals with phenylketonuria may need to monitor their intake of this additive.
• In the FDA pregnancy category C. This means that it is not known whether this medication will harm an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant or could become pregnant during treatment.
• It is not known whether this medication passes into breast milk. Do not take without first talking to your doctor if you are breast-feeding a baby.
• Has not been approved by the FDA for use by children younger than 18 years of age.

Maxalt Dosage Method

• Take tablets exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.
• Take each oral dose with a full glass of water.
• The orally disintegrating tablets do not need to be taken with water or any other liquid. The tablet should be removed from the outer pouch and blister pack with dry hands, immediately before taking the pill. The tablet should then be placed on the tongue, where it will dissolve and be swallowed with the saliva.
• May be taken with or without food.
• Take one tablet as soon as you notice symptoms of a migraine, or at any time during an attack.
• If your symptoms improve only partially, or if they go away and then return, you can take another dose of rizatriptan unless your doctor directs otherwise. The second dose may be taken 2 hours or more after the first one. Never take more than 30 mg in any 24-hour period. If you are also taking propranolol (Inderal), no more than 15 mg should be taken in any 24-hour period, unless specifically directed otherwise by your doctor.
• Store at room temperature away from moisture, heat, light, and the reach of children.
• Throw away any unused medicine on the expiration date.

Miss a dose: Problems?

Since this medication is taken to treat migraine headaches as they occur and not to prevent them, missing a dose is not a problem. Take only the doses you need, according to your doctor's instructions.

Maxalt Overdose?

• Seek emergency medical attention.
• Symptoms of an overdose may include dizziness, sleepiness, a slow heartbeat, and vomiting.

Avoid During Treatment

• Do not take this medication if the headache you are experiencing is not like other migraines that you have had.
• Never take more of this medication than is prescribed by your doctor.

Maxalt Side Effects

• If you experience any of the following serious side effects, stop taking this medication and seek emergency medical attention:
  • an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives)
  • chest pain, tightness, pressure, and/ or heaviness
  • neck, throat, or jaw pain, tightness, or pressure
  • an irregular heartbeat
• Other, less serious side effects may be more likely to occur. Continue to take this medication and talk to your doctor if you experience:
  • nausea
  • dry mouth
  • drowsiness or dizziness
  • numbness, tingling, flushing, warmth, redness, or heaviness in a body part
• Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs to avoid while undergoing treatment

• Do not take this medication if you have taken:
  • a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), tranylcypromine (Parnate), or phenelzine (Nardil) in the last 14 days
  • another 5-HT agonist in the last 24 hours-5-HT agonists include almotriptan (Axert), frovatriptan (Frova), sumatriptan (Imitrex), naratriptan (Amerge), and zolmitriptan (Zomig, Zomig-ZMT)
  • an ergot-based medication within the last 24 hours--ergot-based medicines include methysergide (Sansert), ergotamine (Ergostat, Ergomar), dihydroergotamine mesylate (D.H.E., Migranal Nasal Spray), and ergotamine combination products (Cafergot, Wigraine, Cafatine-PB, and others)
• This medication may be dangerous if it is taken with any of the drugs listed above.
• Before taking this medication, tell your doctor if you are taking:
  • a selective serotonin reuptake inhibitor (SSRI) such as fluoxetine (Prozac), fluvoxamine (Luvox), paroxetine (Paxil), sertraline (Zoloft), or citalopram (Celexa)
  • propranolol (Inderal)
• You may not be able to take this medication, or you may require a special dosage or monitoring during treatment if you are taking any of the medicines listed above.
• Drugs other than those listed here may also interact. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products.

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